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. 2018 Sep 19;9:2121. doi: 10.3389/fimmu.2018.02121

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Copyright © 2018 Chen, Chang, Li, Huang, Yang, Lai, Huang, Wang, Wu, Zhao, Bellanti, Zheng and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The expression of metalloproteinases (MMPs) and IL-17AR in CRS. (A) The mRNA expression levels of MMP-2, MMP-7, and MMP-9 were expressed relative to the expression level of β2 microglobulin (β2M) reference gene. (B) The protein expression levels of MMP-7 and MMP-9 were assayed by ELISA. (C) The co-expression of IL-17AR and MMP-9 in the nasal tissues from the CRSwNP patients. IL-17AR, MMP-9, and Nuclei were stained in red, green, and blue, respectively by Immunofluorescence. Arrows show IL-17AR/MMP-9 double-positive cells (magnification, 400 ×). ^*P < 0.05; ^**P < 0.01; ^***P < 0.001; ns, P > 0.05.