TABLE 1.
S. flexneri genes differentially regulated during infection of Henle-407 cells with exogenous 20 mM formate
| Carriage location and gene |
Function | Fold change |
|---|---|---|
| Virulence plasmid | ||
| ipaJ | Host protein N-myristoylation | 2.3 |
| icsA/virG | Actin-mediated intercellular spread | 2.1 |
| ipgD | Host phosphoinositide metabolism | 2.1 |
| ccdB | Plasmid maintenance | −2.1 |
| Chromosome | ||
| yjhA | Hypothetical protein | 3.3 |
| yccJ | Hypothetical protein | 2.5 |
| yhaH | Putative cytochrome | 2.3 |
| rfbE | Polysaccharide biosynthesis | 2.3 |
| melR | Regulator of melibiose operon | 2.1 |
| ybeK | Putative tRNA synthetase | 2.1 |
| yjhT | Hypothetical protein | 2.1 |
| yhiO | Hypothetical protein | 2.0 |
| proV | Osmotic regulation | −2.1 |
| Rnd | RNase D | −2.2 |
| S2640 | Hypothetical protein | −2.3 |
| yebJ | Hypothetical protein | −2.4 |
| ybaN | Hypothetical protein | −2.6 |