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Quantification of [11C]CEP-32496 in A375 xenografts. Time–activity curves (TACs) of [11C]CEP-32496 in mice preinjected with and without the P-glycoprotein/breast cancer resistance protein inhibitor GF-120918. Data are expressed as means ± standard error of mean (SEM) from 4 tumor-bearing mice per group. Comparisons were performed using 1-way analysis of variance test. ns indicates no statistically significant.
