Table 1.
Biodistribution of [11C]CEP-32496 Radioactivity at 30 and 60 Minutes After the Radiotracer Injection in Nude Mice-Bearing BRAFV600E-Mutation Melanoma.a
| Tissue | 30 Minutes | 60 Minutes |
|---|---|---|
| Blood | 1.75 ± 0.45 | 1.31 ± 0.02 |
| Heart | 3.33 ± 0.11 | 4.69 ± 0.20 |
| Lung | 3.45 ± 0.20 | 5.16 ± 0.34 |
| Liver | 19.08 ± 0.71 | 25.23 ± 0.57 |
| Pancreas | 5.24 ± 0.19 | 6.97 ± 0.33 |
| Spleen | 2.20 ± 0.07 | 3.35 ± 0.15 |
| Kidney | 6.82 ± 0.27 | 9.77 ± 0.45 |
| Small intestine | 33.79 ± 1.23 | 22.30 ± 3.18 |
| Large intestine | 4.88 ± 0.25 | 3.44 ± 0.22 |
| Skin | 2.45 ± 0.09 | 2.57 ± 0.18 |
| Tumor | 1.79 ± 0.07 | 1.85 ± 0.09 |
| Muscle | 2.03 ± 0.11 | 2.63 ± 0.05 |
| Brain | 0.13 ± 0.00 | 0.15 ± 0.00 |
a Data are expressed as the mean %ID/g tissue with the standard error of mean (n = 4 mice/group).