Figure 6.

Tn antigen expression impairs MUC2 expression in human colorectal cancer tissues. A, Tn antigen and MUC2 expression were detected simultaneously in human CRC tissues (n = 48) by multiple immunohistochemical staining. There was an inverse correlation between Tn antigen and MUC2 expression. Scale bar, 100 μm. B, FACS analysis of MUC2 protein expression in LS174T cells transfected with WT Cosmc or blank vector. C, Quantification of MUC2 protein expression in LS174T cells by FACS. **P < .01