Figure 4.

OTUB1‐isoform2 promotes ovarian tumour cell migration. A, Cell migration ability was evaluated using a wound‐healing assay; images of SKOV3 cells transfected with OTUB1‐isoform2 or pcDNA3.1 control were taken at 0 and 24‐h post‐scratch. The percentage of closed distances of healed wounds after 24 h was calculated under the microscope (scale bars = 200 μm). Data are shown as the mean SD of three replicates. The P value was illustrated. B, Cell migration ability was evaluated using a wound‐healing assay; images of A2780 cells transfected with OTUB1‐isoform2 or pcDNA3.1 control were taken at 0 and 24‐h post‐scratch. The percentage of closed distances of healed wounds after 24 h was calculated under the microscope (scale bars = 200 μm). Data are shown as the mean SD of three replicates. The P value was illustrated