Figure 8.
BMSCs in combination with miR‐124a protect kidney tissue from impairment. SD rats were divided into control group (Con), BMSCs group (B/Con, 3 × 106 BMSCs), diabetic model group (DN), mock (M/DN), miR‐124a mimics (m/DN) and miR‐124a inhibitors (i/DN). A, The morphology of rat kidney was observed by HE staining in different groups. B, The extent of glomerular injury was observed by PAS staining in different groups. C, The mRNA expression levels of nephrin, podocin, and CD2AP were analysed by qRT‐PCR assay (**P < .01 vs B/Con; ^P < .05 or ^^P < .01 vs DN; &&P < .01 m/DN vs M/DN; ##P < .01 i/DN vs M/DN). D, The protein expression levels of nephrin, podocin and CD2AP were detected by Western blot assay