Table 1.
Fibroblasts culture | LMNA mutation | Age of donor at biopsy | Gender | Passage number | Used for |
---|---|---|---|---|---|
CONTROL 1 | None | 15 | F | 18–22 | MA,WB, IF, PLA |
CONTROL 2 | None | 65 | M | 14–18 | MA, IF, PLA |
APS (atypical progeria syndrome) | P4R | 17 | F | 14–15 | WB, PLA |
MADA (Mandibuloacral dysplasia A type) | R527H | 50 | M | 13–14 | WB, PLA |
HGPS (Hutchinson–Gilford progeria syndrome)1 | G608G | 6 | M | 20–24 | MA, WB, IF, PLA |
HGPS (Hutchinson–Gilford progeria syndrome)2 | G608G | 3 | F | 12–14 | MA |
EDMD2 (Emery‐Dreifuss muscular dystrophy) | Y259D | 11 | F | 14–16 | WB, PLA |
IF: immunofluorescence; MA: microarray; PLA: proximity ligation assay; WB: western blot analysis.