Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A Diagram, which Depicts Four Methods of NO Release, Leading to Increased Blood Flow: (a) nitric oxide is postulated to be released from RRx‐001 (formula shown below) directly via a Nef‐like reaction; (b) RRx‐001 binds to the betaCys93 residue on haemoglobin, which accelerates the formation of nitric oxide from deoxyhemoglobin in RBCs; (c) spontaneous release of nitric oxide from a NONOate in aqueous media; (d) production of NO via eNOS in the endothelium
