Figure 2.

A, Blood Smear for Aggregation Studies Obtained from Heparinized Human Blood Untreated or Treated with Vehicle, RRx‐001 (10 mg/kg) or Dextran 500 kDa (10 mg/kg in Sterile Saline, Positive Control). From left to right vehicle‐treated blood, RRx‐001‐treated blood and Dextran‐treated blood. Clumping and rouleaux formation is only seen with Dextran, the positive control; B, RBC aggregation index of human blood untreated, or treated with Vehicle, RRx‐001 (10 mg/kg) or Dextran 500 kDa (10 mg/kg in sterile saline, positive control). RBC aggregation index was unchanged between untreated blood, vehicle‐treated blood and RRx‐001 treated blood. Only Dextran, the positive control, showed a significant (P < 0.05) increase in RBC clumping and aggregation (far right panel)