Figure 4.

Platelet Aggregation of Platelet‐rich Plasma Measured using % of Light Transition. Effects of RRx‐001 and DETA‐NONO in the absence (left panel) and in the presence (right panel) of the nitric oxide scavenger, CPTIO. Each point represents the mean ± SEM of all experiments. The platelets were incubated with test drugs for before stimulation with ADP, and aggregation was monitored thereafter. Results are expressed as percent inhibition of aggregation relative to the untreated platelets CPTIO: 5,2‐(4‐carboxyphenyl)‐4,4,5,5‐tetramethylimidazoline 1‐oxyl 3‐oxide