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. 2018 Sep 25;8:14353. doi: 10.1038/s41598-018-32771-x

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Validations of differently expressed genes in RNA-seq with qPCR. y-axis: the fold change of gene expression, x-axis: the gene name. PTK2B = Protein-tyrosine kinase 2-beta, BMP3 = Bone morphogenetic protein 3, DTX4 = E3 ubiquitin-protein ligase DTX4, COX4 = Cytochrome c oxidase subunit 4, ATP4A = Potassium-transporting ATPase alpha chain 1, CPLA2 = Cytosolic phospholipase A2, ATP2B4 = Calcium-transporting ATPase 4, α-NKA = Na⁺/K⁺-ATPase alpha subunit, KCTD13 = Potassium channel tetramerization domain containing 13, PTK6 = Protein-tyrosine kinase 6, Hsp70 = Heat shock 70 kDa protein and Hsp90 = Heat shock 90 kDa protein.