Figure 7.

NGFFYamide causes relaxation of in vitro acetylcholine-contracted apical muscle preparations from A. rubens. A representative recording is shown, with 10⁻⁶ M NGFFYamide causing transient partial reversal of the contracting action 10⁻⁶ M acetylcholine (ACh). Application of ACh and NGFFYamide are labeled with upward pointing arrowheads and washing of the preparation is labeled with a downward pointing arrowhead. The graph shows the mean (± s.e.m.) relaxant effect of NGFFYamide when tested at a concentration of 10⁻⁶ M (n = 4).