Table 1.
Demographic and PADI4 polymorphisms data of 127 patients with septic shock
| Variables | ICU mortality | P value | |
|---|---|---|---|
| Yes (n = 86) | No (n = 41) | ||
| Age, (years) | 66.0 (58.0‐73.0) | 63.0 (50.0‐73.5) | .337 |
| Male, n (%) | 45 (52.3) | 27 (65.8) | .212 |
| APACHE II score, n (%) | 19.7 ± 6.6 | 15.9 ± 6.7 | .003 |
| SOFA score, n (%) | 10.0 (8.7‐12.0) | 8.0 (7.0‐10.5) | <.001 |
| Sepsis focus, n° (%) | |||
| Respiratory | 55 (64.0) | 18 (44.0) | .221 |
| Abdominal | 16 (18.6) | 13 (31.7) | |
| Urinary | 5 (5.8) | 5 (12.2) | |
| Others | 10 (11.6) | 5 (12.1) | |
| PADI4 (rs11203366), n (%) | |||
| GG | 18 (21.0) | 6 (14.6) | .642 |
| AG | 36 (41.8) | 20 (48.8) | |
| AA | 32 (37.2) | 15 (36.6) | |
| PADI4 (rs2240340), n (%) | |||
| TT | 18 (21.0) | 4 (9.8) | .219 |
| CT | 37 (43.0) | 23 (56.1) | |
| CC | 31 (36.0) | 14 (34.1) | |
| PADI4 (rs1748033), n (%) | |||
| TT | 10 (11.6) | 3 (7.3) | .697 |
| CT | 37 (43.0) | 20 (48.8) | |
| CC | 39 (45.4) | 18 (43.9) | |
APACHE II, Acute Physiology and Chronic Health Evaluation; ICU: intensive care unit; PAD 4: peptidylarginine deiminase 4; SOFA: Sequential Organ Failure Assessment.
Data are expressed as the mean ± SD median (including the lower and upper quartiles) or percentage.