Table 1.
Spearman partial correlation coefficients (ρ) and 95% confidence intervals (CI) to depict associations between participant age and human periostin mRNA expression in sWAT and vWAT following adjustment for body mass index (BMI), or lipid and liver function parameters
Variable | human periostin mRNA expression in human sWAT | human periostin mRNA expression in human vWAT | ||
---|---|---|---|---|
ρ (95% CI) | p‐Value | ρ (95% CI) | p‐Value | |
Age (n = 471) | 0.10 (0.1; 0.18) | 0.03 | 0.13 (0.04; 0.21) | 0.005 |
Age (adj. for BMI; n = 471) | 0.06 (−0.02; 0.15) | 0.14* | 0.09 (0.01; 0.18) | 0.03 |
Age (adj. for body weight; n = 469) | 0.06 (−0.02; 0.15) | 0.17* | 0.09 (0.01; 0.18) | 0.04 |
Age (adj. for triglycerides; n = 342) | 0.06 (−0.04; 0.17) | 0.20* | 0.09 (−0.01;0.19) | 0.08* |
Age (adj. for total cholesterol; n = 338) | 0.07 (−0.02; 0.18) | 0.15* | 0.11 (0.01; 0.19) | 0.03 |
Age (adj. for LDL cholesterol; n = 282) | 0.09 (−0.02; 0.20) | 0.12* | 0.14 (0.03; 0.26) | 0.01 |
Age (adj. for HDL cholesterol; n = 281) | 0.07 (−0.04; 0.18) | 0.24* | 0.12 (0.01; 0.24) | 0.03 |
Age (adj. for ASAT; n = 395) | 0.13 (0.03; 0.23) | 0.008 | 0.13 (0.03; 0.23) | 0.007 |
Age (adj. for ALAT; n = 461) | 0.07 (−0.02; 0.16) | 0.10* | 0.10 (0.01;0.19) | 0.02 |
Age (adj. for GGT; n = 456) | 0.10 (0.01; 0.19) | 0.02 | 0.12 (0.03; 0.21) | 0.008 |
Age (adj. for fasting glucose; n = 439) | 0.12 (0.04; 0.22) | 0.007 | 0.14 (0.05; 0.23) | 0.002 |
Age (adj. for CRP; n = 461) | 0.06 (−0.02;0.16) | 0.16* | 0.09 (0.01; 0.18) | 0.04 |
Age (adj. for creatinine; n = 462) | 0.10 (0.01; 0.19) | 0.02 | 0.12 (0.04; 0.22) | 0.005 |
Age (adj. for leukocytes; n = 466) | 0.09 (0.02; 0.17) | 0.05 | 0.12 (0.02; 0.20) | 0.01 |
*Adjustment for biomarker leads to loss of statistical significance.