Figure 2.

IGF2 is the host gene of miR‐483‐3p. A,The mRNA and protein expression levels of IGF2 were lower in HSCR tissues than controls determined by qRT‐PCR and Western blot. (*P < 0.05) B, The 293T and SH‐SY5Y cells were transfected with IGF2 siRNA, and then, the expression of miR‐483‐3p was reduced in both cell lines. (***P < 0.05) C, Co‐transfection of miR‐483‐3p mimics partially rescued the IGF2 siRNA‐mediated decrease in cell migration (***P < 0.05) and proliferation (**P < 0.05). Absorbance at 450 nm was presented as mean ± SE. *means significant difference (P < .05)