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. 2018 Sep 25;8:14328. doi: 10.1038/s41598-018-31988-0

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Whole-brain eigenvector centrality group comparisons. Within group effect: EC reductions in PD-ON compared to PD-OFF. Between group effects: EC increases in PD-OFF compared to controls and EC decreases in PD-ON compared to controls. 3D overlay is shown. The boxplots show EC values in the peaks of significant clusters (x, y, z MNI coordinates). p < 0.05 FWE at cluster level. Brain images displayed in neurological convention (left hemisphere on the left of the image). Abbreviations: L: left; R: right; SMG: Supramarginal Gyrus; STG: Superior Temporal Gyrus; CG: Central Gyrus. Unthresholded results for the displayed contrasts can be found on NeuroVault https://neurovault.org/collections/3976/.