. 2018 Sep 25;9:3911. doi: 10.1038/s41467-018-06388-7

Table 2.

Parameter values for fits of the single transducer population gating spring model

	AEG ♀	QUI ♀	GAM ♀	AEG ♂	QUI ♂	GAM ♂
Channel number, N	544.6***	801.8***	764.1***	106.9***	73.8***	60.5***
Channel gating force, z (fN)	23.7***^,†	22.1***^,†	34.4***^,†	51.0***	56.4***	144.9***
K_INFINITY (µN/m)	93.8***^,††	103.1***^,††	147.8**^,††	178.3***^,††	190.6***^,††	283.8**^,††
K_STEADY (µN/m)	82.4***^,†	85.7***^,†††	112.7***^,†††	147.7***^,†	159.1***^,†	208.1***^,†
K_GS (µN/m)	11.5***^,†††	17.3**^,†††	35.1***^,†††	30.5***^,†††	31.5**^,†††	75.8***^,†††
Extent of nonlinearity	0.202*^,††	0.235*^,††	0.379***^,††	0.096*^,†††	0.076*^,^††	0.276***^,†††
CAP₅₀ (nm)	1079***	741*^,†	1425***^,^†	180***	145*	135***
λ₉₀ (nm/mdeg)	1023.9/58.7	1098.3/62.9	705.0/40.4	476.1/27.3	430.9/24.7	167.6/9.6

Function fit values for a single transducer population fit to median stiffness values (unified to a measurement height of 1 mm above flagellar base, see Supplementary Table 1 for flagellar lengths for each sex and species) for female and male Ae. aegypti (AEG), Cx. quinquefasciatus (QUI) and An. gambiae (GAM). N is the estimated number of transducer channels and z is the force change following the opening of a transducer channel for one gating spring. Here, K_INFINITY is the asymptotic flagellar stiffness at large displacements, whilst K_STEADY is the combined linear elasticity of the flagellar joint and neurons of the flagellar receiver. K_GS (the gating spring stiffness) was calculated as K_INFINITY − K_STEADY and so provides information on transducer module mechanical integrity. The extent of nonlinearity indicates the degree to which the system is nonlinear. CAP₅₀ values refer to the minimum flagellar displacement required to produce an antennal nerve response of 50% of the maximum response. λ₉₀ values refer to the displacement at which 90% of the transducers are predicted to be open. Significant differences between conspecific female and male mosquitoes are starred (ANOVA on ranks; *p < 0.05; **p < 0.01; ***p < 0.001). Significant differences between mosquitoes of the same sex but of different species are also highlighted (ANOVA on ranks; ^†p < 0.05; ^††p < 0.01; ^†††p < 0.001)