Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Sep 25;8:14327. doi: 10.1038/s41598-018-32309-1

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Effect of Carved on photomicrographs of liver tissues stained with Masson Trichome stain. Sections of (C,D) CCl₄ intoxicated group show extensive fibrosis and strong histochemical reaction for collagen fibers in the portal triad and around the hepatic lobules (arrows), relative to sections of (A,B) normal group showing no histochemical reaction for collagen fibers. Sections of animals treated with (E,F) Carved show a weak histochemical reaction for collagen fibers (arrows) (x100, scale bar = 46.2μm; x400: scale bar = 11.6 μm). Panel (G) represents percentage area of collagen content in liver tissues. Values are expressed as mean ± S.D (n = 3sections/rat/group). Statistical analysis was carried out using one way ANOVA followed by Tukey’s post hoc test, P < 0.05. As compared to (*) control group or (#) CCl₄ intoxicated group. Carved treatment (10 mg/kg, p.o, daily) started 2 weeks post CCl₄ (2 ml/kg, i.p) initiation until week 8. Carved: Carvedilol; CCl₄: carbon tetrachloride.