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. 2018 Sep 19;9:428. doi: 10.3389/fpsyt.2018.00428

Table 2.

Characteristics of included studies.

References DSM-IV diagnosis Treatment duration in weeks Dose (mg) Sample size Age mean (SD) Male (%)
Baseline Follow-up
Varenicline Placebo Varenicline Placebo Varenicline Placebo Varenicline Placebo
Williams et al. (33) SCZ/SCA 12 0.5 × 3days, 1 × 4days, 2/day thereafter 84 43 61 37 40.2 (11.9) 43 (10.2) 77.4 76.7
Jeon et al. (43) SCZ 8 0.5 × 3days, 1 × 4days, 2/day thereafter 30 30 23 22 41.1 (8.9) 41.5 (8.8) 86.7 96.7
Hong et al. (46) SCZ/SCA 8 0.5 × 1week, 1 × 7week 20 23 19 21 43 (11) 41.5 (11.4) 65 60.9
Weiner et al. (19) SCZ/SCA 12 1/day 4 5 4 4 ND ND ND ND

SD, standard deviation; SCZ, schizophrenia; SCA, schizoaffective; d, days.