Table 1.
Control C (n = 35) | Elderly (>70) (n = 28) | p value | |
---|---|---|---|
Sex (n of men (%)) | 23 (66.6) | 14 (50) | 0.193 |
Age (years) | 38.1 ± 0.6 | 80.8 ± 1.1 | <0.001 |
Weight (kg) | 74.8 ± 5.0 | 70.8 ± 2.5 | 0.859 |
BMI | 24.4 ± 0.6 | 27.4 ± 0.6 | 0.161 |
Waist‐to‐hip ratio | 0.86 ± 0.03 | 0.92 ± 0.01 | 0.083 |
Total body fat (%) | 26.3 ± 2.1 | 37.9 ± 1.4 | 0.002 |
Glucose (mmol/L) | 4.73 ± 0.15 | 5.93 ± 0.23 | 0.048 |
Insulin (pmol/L) | 38.7 ± 8.9 | 123.8 ± 18.6 | 0.023 |
HOMA‐IR | 0.45 ± 0.11 | 1.81 ± 0.28 | 0.011 |
Bilirubin (mmol/L) | 8.00 ± 1.32 | 12.69 ± 0.89 | 0.461 |
AST (U/L) | 28.4 ± 2.6 | 22.1 ± 1.3 | 0.579 |
ALT (U/L) | 40.9 ± 8.9 | 19.2 ± 1.5 | 0.007 |
Triglycerides (mmol/L) | 1.07 ± 0.21 | 1.21 ± 0.11 | 0.856 |
Total cholesterol (mmol/L) | 4.68 ± 0.31 | 5.08 ± 0.16 | 0.813 |
HDL cholesterol (mmol/L) | 1.36 ± 0.07 | 1.33 ± 0.06 | 0.951 |
LDL cholesterol (mmol/L) | 2.91 ± 0.32 | 3.17 ± 0.14 | 0.852 |
TNFα (pg/ml) | 2.91 ± 0.28 | 4.96 ± 0.61 | 0.003 |
MCP−1 (pg/ml) | 119.9 ± 7.0 | 252.1 ± 30.3 | <0.001 |
Parameters are expressed as mean ± SEM unless specified. P values were calculated using Student's t test for parametric data. Bold lettering is shown when p < 0.05.
ALT, alanine transaminase; AST: aspartate transaminase; BMI: body mass index; HDL: high‐density lipoprotein; HOMA‐IR: homeostasis model assessment of insulin resistance; LDL: low‐density lipoprotein; MCP‐1, monocyte chemoattractant protein‐1; TNFα: tumor necrosis factor‐α.