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. 2018 Sep 25;8:14351. doi: 10.1038/s41598-018-32713-7

Table 1.

A summary of the tested methods with a description of their performance.

Spectral denoising technique PROS CONS
Savitzky-Golay Very low signal distortion, short computational time SNR gain lower than one order of magnitude, two parameters optimization
Fourier-Transform Very low signal distortion, easy to implement, short computational time, easy to optimize SNR gain lower than one order of magnitude
PCA Significant SNR gain and reasonable signal distortion Medium difficulty algorithm, time and memory consuming computations
MNF Significant SNR gain and reasonable signal distortion Difficult algorithm, hard to implement, time and memory consuming computations
Wavelets Very low signal distortion SNR gain around one order of magnitude, time consuming calculation and optimization
Spatial denoising technique PROS CONS
Fourier-Transform Good pSNR gain, high SSIM, easy to implement, reasonable computation time, easy to optimize Image artifacts
Mean Filter Good SSIM, easy to implement, low computational time Mild pSNR gain
Median Filter Good SSIM, easy to implement, low computational time Mild pSNR gain
Gauss Filter Good SSIM, easy to implement, low computational time Mild pSNR gain
Weighted Mean Filer Good SSIM, easy to implement, low computational time Mild pSNR gain
Wavelets Noticeable pSNR gain Low pSNR gain and SSIM, time consuming calculation and optimization, image artifacts
Deep Neural Networks Reasonable pSNR and SSIM Difficult algorithm to train