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. 2018 Aug 27;35:394–404. doi: 10.1016/j.ebiom.2018.08.047

Fig. 3.

Fig. 3

Various actions of metformin in human tissues. Aside from its classic application in controlling hyperglycaemia, the use of metformin is being expanded significantly, from anti-cancer therapy to regulation of gut microbiota. However, the various applications of metformin also highlight the vast range of different possible actions of metformin in different cells/tissues.