Table 5.
Top canonical pathways of up-regulated genes involved in immunological processes as demonstrated by interactive pathway analysis (IPA)
| DAN | ILI | BOR |
|---|---|---|
|
1. Acute phase response signaling 1.94E−05a, 19/200 (0.095)b |
1. Agranulocyte adhesion and diapedesis 8.29E−10, 43/189 (0.228) |
1. Agranulocyte adhesion and diapedesis 3.52E−12, 27/189 (0.143) |
|
2. Agranulocyte adhesion and diapedesis 1.95E−05, 15/133 (0.113) |
2. Granulocyte adhesion and diapedesis 1.28E−07, 37/177 (0.209) |
2. Granulocyte adhesion and diapedesis 5.19E−09, 22/177 (0.124) |
|
3. Interferon signaling 5.66E−05, 17/180 (0.308) |
3. Leukocyte extravasation signaling 3.07E−07, 39/198 (0.197) |
3. Leukocyte extravasation signaling 5.71E−09, 24/210 (0.114) |
|
4. Clathrin-mediated endocytosis signaling 2.22E−04, 10/81 (0.123) |
4. iNOS signaling 1.29E−06, 15/44 (0.341) |
4. Production of nitric oxide and reactive oxygen species in macrophages 1.2E−07, 21/193 (0.109) |
|
5. Production of nitric oxide and reactive oxygen species in macrophages 3.19E−05, 28/193 (0.145) |
5. Interferon signaling 1.48E−06, 13/34 (0.382) |
5. Caveolar-mediated endocytosis signaling 5.82E−07, 12/71 (0.169) |
ap-Value
bPathway ratio