Table 1.
Model parameter values used in base case and sensitivity analyses
| Symbol | Primary analysis | Sobol rangeb |
|
|---|---|---|---|
| Population parameters | |||
| Difference in transmission (either):a | |||
| Within-group mixing (’contact’) | χ | 0.65–0.95 | 0.65–1.54 |
| Relative susceptibility of group L to group H (’susceptibility’) | η | 0.65–0.95 | 0.65–1.54 |
| Quantity of out-group mixing relative to within-group mixing of group H (’integration’) | ξ | 0.05–0.25 | 0.05–0.25 |
| Relative vaccine uptake in group H to group L | VH/VL | 1.0 | 0.70–1.43 |
| Epidemiological parameters | |||
| Basic reproduction number [48, 49] | R 0 | ||
| Influenza | 1.8 | 1.5–4.0 | |
| Rubella | 6.5 | 5.0–8.0 | |
| Pre-infectious period (days) [50] | σ | ||
| Influenza | 2.6 | 2.6 | |
| Rubella | 14.0 | 14.0 | |
| Infectious period (days) [50] | γ | ||
| Influenza | 4.0 | 4.0 | |
| Rubella | 11.0 | 11.0 | |
aOne parameter value set to 1.0 whilst the other adjusted over the ‘primary analysis range’
bRanges were set so the mid value is the ‘base case’, which was 1.0 (no difference) for factors which vary for group L relative to group H