Table 2.
Associations of epidemiological factors to prevalence of Streptococcus pneumoniae in middle ear fluid in children with AOM - univariate and multivariate analysis
| Characteristics | Univariate analysis | Multivariate model | ||
|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | |
| Age (yr) | 0.8 (0.61–1.06) | 0.13 | ||
| Male sex | 1.6 (0.86–3.03) | 0.14 | ||
| Sibling possessing | 0.96 (0.53–1.72) | 0.88 | ||
| DCC/school attendance | 0.93 (0.50–1.73) | 0.83 | ||
| Bilaterality | 1.38 (0.76–2.52) | 0.29 | ||
| Category of AOM:TF/R | 1.28 (0.67–2.42) | 0.46 | 0.05 (0.01–0.17) | 0.062 |
| CRP (mg/L) | 1.05 (0.97–1.14) | 0.23 | 1.12 (1.01–1.25) | 0.039* |
| WBC (G/L) | 1.21 (1.07–1.36) | 0.002* | 1.22 (1.05–1.42) | 0.009* |
| Ongoing antibiotic therapy at the admission to hospital | 0.54 (0.24–1.21) | 0.14 | 0.07 (0.006–0.87) | 0.038* |
| Antipneumococcal vaccination | 0.42 (0.14–1.2) | 0.10 | 0.059 (0.002–1.57) | 0.091 |
*Statistic significance; R recurrent AOM, TF treatment failure AOM, N new case AOM, DCC day care center, CRP C-reactive protein, WBC white blood cells