Skip to main content
. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Plast Reconstr Surg. 2018 Oct;142(4):952–961. doi: 10.1097/PRS.0000000000004759

Figure 1. Nerve regeneration within long and short isografts.

Figure 1

A) Analysis was performed at consistent distances (1 & 2cm) from the spinal cord and proximal suture site to compare regeneration within grafts after 8 weeks, such that the only variable was graft length. B) Axon counts were reduced in the long (6cm) compared to short (2cm) grafts. C) While percent nerve did not differ based on graft length, long grafts had greater percent debris (D) compared to short grafts. Myelin width (E) and fiber width (F) did not differ between grafts. G) Binning of fiber widths showed that long grafts shifted toward smaller widths compared to short grafts. H) Applying retrograde tracer at the 2cm distance, the number of regenerating motoneurons labeled was decreased in long compared to short grafts; the uninjured nerve metric denotes the baseline number of motoneurons. * p<0.05, n=8 per group, dashed line indicates the uninjured nerve metric.