Table 3.
N | Median survival (month; 95% CI) | p values | |
---|---|---|---|
Gender | 0.13 | ||
Male | 59 | 11.0 (7.6–14.4) | |
Female | 11 | 8.0 (1.5–14.5) | |
Age, y | 0.033 | ||
<50 | 22 | 17.0 (17.0–17.0) | |
≥ 50 | 48 | 8.0 (6.3–9.7) | |
AFP, ng/L | 0.438 | ||
≤ 20 | 14 | 8.0 (2.9–13.1) | |
21–399 | 18 | 14.0 (11.9–16.1) | |
≥ 400 | 38 | 8.0 (5.6–10.4) | |
Additional treatment after RT | 0.00 | ||
SBRT alone | 20 | 3.0 (1.1–4.9) | |
SBRT+TACE | 46 | 12.0 (8.9–15.1) | |
Radiation Dose | 0.376 | ||
≤ 27.5Gy | 4 | 3.0 (0–8.9) | |
30-35Gy | 25 | 8.0 (6.8–9.2) | |
≥ 40Gy | 41 | 11.0 (7.7–14.3) | |
Origination of PVTT | 0.079 | ||
Right branch | 49 | 8.0 (5.8–10.2) | |
Left branch | 21 | 13.0 (8.5–17.5) | |
Type of tumor thrombosis | 0.107 | ||
Type II | 42 | 8.0 (5.5–10.5) | |
Type III | 27 | 14.0 (8.6–19.4) | |
Response (3 m after SBRT) | 0.000 | ||
CR | 6 | * | |
PR | 43 | 13.0 (10.0–16.0) | |
SD | 4 | ** | |
PD | 9 | 4.0 (1.1–6.9) |
Abbreviations: SBRT Stereotactic body radiotherapy, AFP Alpha-fetoprotein, RT Radiotherapy, CR Complete response, PR Partial response, SD Stable disease, PD Progressive disease. * The medium survival for patients with CR was not reported because only two patients died in 7th and 11th month. The other four patients were alive, 1 patient with 15 months follow-up, 3 patients with 16 months follow-up after SBRT. ** In the four patients with SD, 3 patients died in the 8th, 8th and 11th month, the other patient was alive with 12 months follow-up