Table 2. Association between mumps complications, hospitalisation, severe outcome and measles-mumps-rubella (MMR) vaccination status in mumps cases, Norway, September 2015–March 2016 (n = 207).
Complication or severe outcome | Doses of MMR vaccinations | Cases with complication | Total cases | % | Adjusteda RR (95% CI) | p-value |
---|---|---|---|---|---|---|
Hospitalisation | 0 | 2 | 9 | 22 | Ref | Ref |
1 | 0 | 13 | 0 | 0.00 (0.00–0.00) | < 0.001 | |
2 | 5 | 184 | 3 | 0.14 (0.03–0.57) | 0.006 | |
3 | 0 | 1 | 0 | 0.00 (0.00–0.03) | < 0.001 | |
Orchitisb | 0 | 4 | 7 | 57 | Ref | Ref |
1 | 0 | 10 | 0 | 0.00 (0.00–0.00) | < 0.001 | |
2 | 12 | 103 | 12 | 0.21 (0.08–0.55) | 0.001 | |
Severe casec | 0 | 4 | 9 | 44 | Ref | Ref |
1 | 0 | 13 | 0 | 0.00 (0.00–0.00) | < 0.001 | |
2 | 15 | 184 | 8 | 0.25 (0.10–0.62) | 0.003 | |
3 | 0 | 1 | 0 | 0.08 (0.01–0.62) | 0.016 |
CI: confidence interval; MMR: measles-mumps-rubella; RR: relative risk.
aAdjusted for age (as continuous variable) and gender except for orchitis, which was adjusted only for age among males.
bProportions and estimations for orchitis were calculated using data only from male cases with known vaccination status: 120 cases.
cA severe case was defined as a case that was hospitalised or presented with any mumps-related complications (e.g. orchitis, meningitis).