Table 1.
Receptor | Agonist | HPV Antigen | Reference |
---|---|---|---|
Prophylactic Assays | |||
TLR2 | Lipopeptide | E7 CTL epitope | (72) |
TLR4 | AS04, LPS derivative | VLP (L1) | (68) |
TLR5 | Flagellin | E6/E7 peptide | (77) |
Therapeutic Assays | |||
TLR3 | Poly (I:C) | E7 peptide | (73) |
TLR3/TLR7 | Resiquimod/Poly (I:C) | E7 DNA | (75) |
TLR7 | Imiquimod | E7-calreticulin DNA | (76) |
TLR7/TLR9 | Imiquimod/CpG | E7 DNA | (74) |
Prophylactic and Therapeutic Assays | |||
TLR2/TLR4 | HMGB1 peptide | E7 DNA | (78) |