Table 3.
Risk factors for the association of autoimmune diseases (AD) in coeliac disease (CD) patients by logistic regression analysis in the whole group of included patients and in gender-age-matched patients.
| All included patients (n = 341) OR (95% CI) |
Gender-age matched patients (n = 172) OR (95% CI) |
|
|---|---|---|
| Age at CD diagnosis | ||
| <40 | 1.0 | — |
| ≥40 | 1.2 (0.7–2.1) | |
| Gender | ||
| Male | 1.0 | — |
| Female | 0.65 (0.3–1.3) | |
| Overweight (BMI ≥ 25 kg/m2) | ||
| No | 1.0 | |
| Yes | 2 (1.1–3.8) | 8.4 (2.9–24.8) |
| Gastrointestinal symptoms leading to CD diagnosis | ||
| No | 1.0 | |
| Yes | 1.2 (0.6–2.3) | 0.6 (0.2–1.6) |
| Severe histological damage (Marsh 3C) | ||
| No | 1.0 | |
| Yes | 0.95 (0.6–1.7) | 0.96 (0.4–2.15) |
| Family history of AD | ||
| No | 1.0 | |
| Yes | 3.7 (1.9–7) | 6.9 (2.2–21.7) |
| Duration of symptoms ≥ 10 years before CD diagnosis | ||
| No | 1.0 | |
| Yes | 2.1 (1.1–3.7) | 19.6 (5.3–73.1) |