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Effect of IL-6 on the polarization of macrophages. The mRNA expression levels of CD86 (a), CD163 (b), and IL-10 (c) were detected by RT-PCR. Immunohistochemical staining analysis (d) showed significantly increased intensity of CD163 staining after culture in IL-6-induced conditioned medium, but not estrogen- or progestin-induced conditioned medium (e). n = 8, ∗ P < 0.05, ∗∗ P < 0.01.
