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8 μ M of (+)-UA decreased cellular ATP content and increased LDH release. (a-b) Cellular ATP level measurement: aP < 0.05, and bP < 0.05, versus control (0 h); (c-d) LDH level measurement: aP < 0.05, versus control (0 h); (e-f) CASP3/7 activity assay: 2-8 μM of (+)-UA did not significantly induce increase in CASP3/7 activity.
