Table 3.

Health Canada approved sublingual immunotherapy tablets [23–26]

	Extract composition	Age indication	Dose initiation	Timing of initiation before pollen season	Daily dose
Oralair®	Five grass pollens: • Cocksfoot • Sweet vernal grass • Rye grass • Meadow grass • Timothy	5–50 years	3 day escalation (from 100 to 300 IR)	16 weeks	300 IR
Grastek®	Timothy grass pollen	≥ 5 years	Full dose	At least 8 weeks	2800 BAU
Ragwitek®	Short ragweed pollen	18–65 years	Full dose	At least 12 weeks	12 Amb a 1-U

	Composition	Age indication	Dose initiation	Timing of initiation	Daily dose
Acarizax™	Standardized allergen extract, house dust mites (D. farinae and D. pteronyssinus)	18–65 years	Full dose	Any time during the year	1 sublingual tablet (12 SQ-HDM*) daily

BAU bioequivalent allergy units, IR index of reactivity, U units

*SQ-HDM is the dose unit for ACARIZAX™. SQ is a method for standardization on biological potency, major allergen content and complexity of the allergen extract. HDM is an abbreviation for house dust mite