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. 2018 Sep 18;9:1045. doi: 10.3389/fphar.2018.01045

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Copyright © 2018 Fu, Fu, Chen, Hu, Quan and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Overexpression of MYCT1 delays the growth of AML xenograft tumors in vivo. HL-60 and KG-1a cells were first subcutaneously implanted into the flanks of BALB/c-nu mice. Mice were given intratumoral injections of Lv-NC or Lv-MYCT1 at day 7, 12, and 17. (A,B) Tumor volumes of AML xenografts in different groups. (C,D) Photographs of the mice bearing AML xenograft tumors (C,D, upper panel) and the isolated tumors (C,D, lower panel). (E,F) Tumor weights of AML xenografts in different groups. ^∗P < 0.05 and ^∗∗P < 0.01 versus HL-Lv-NC or KG-Lv-NC cells.