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. 2018 Sep 19;9:940. doi: 10.3389/fphar.2018.00940

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Copyright © 2018 Konings, Brentjens, Delvoux, Linnanen, Cornel, Koskimies, Bongers, Kruitwagen, Xanthoulea and Romano.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of steroids (mainly estrogens) and intracrine networks in central nervous system, lungs, digestive system, uterus and bone. Italics and by brackets are those metabolism/reactions that need conformation by independent authors (because validated at the mRNA level only or in few studies). * EC, epithelial cells; **SMC, smooth muscle cells; ^#Chol, cholesterol. The drawing was kindly generated by Dr. Margaretha A. Skowron (Department of Urology, University Düsseldorf, Germany) for this review.