Table 2.
The 2.5th and 97.5th Percentiles (Reference Range) of TSH, FT4, and FT3 in TPOAb Negative Pregnant Women
| Reference populationa | Also excluding TgAb-positiveb | |
|---|---|---|
| Plasma TSH, mU/L | ||
| n | 2577 | 2430 |
| 2.5th percentile [95% CI] | 0.39 [0.36, 0.44] | 0.41 [0.36, 0.45] |
| Median [95% CI] | 1.19 [1.17, 1.22] | 1.19 [1.16, 1.22] |
| 97.5th percentile [95% CI] | 2.70 [2.62, 2.80] | 2.70 [2.60, 2.79] |
| Plasma FT4, pmol/L | ||
| n | 2576 | 2429 |
| 2.5th percentile [95% CI] | 10.3 [10.2, 10.4] | 10.3 [10.2, 10.4] |
| Median [95% CI] | 12.6 [12.5, 12.6] | 12.5 [12.5, 12.6] |
| 97.5th percentile [95% CI] | 15.6 [15.3, 16.0] | 15.6 [15.3, 16.0] |
| Plasma FT3, pmol/L | ||
| n | 2577 | 2430 |
| 2.5th percentile [95% CI] | 4.00 [3.97, 4.03] | 4.00 [3.97, 4.03] |
| Median [95% CI] | 4.90 [4.87, 4.92] | 4.90 [4.87, 4.93] |
| 97.5th percentile [95% CI] | 6.00 [5.91, 6.10] | 6.00 [5.91, 6.10] |
Mean gestational week, 18.5; SD, 1.3.
a
Population characteristics: singleton pregnancies, not TPOAb positive (i.e., TPOAb <4.11 IU/mL), not current user of thyroid medication or thyroid disrupting medication, and not in vitro fertilization.
b
Additionally excluding TgAb positive (>4.11 IU/mL according to manufacturer cutoff), n = 147.
FT3, free triiodothyronine; FT4, free thyroxine; TSH, thyrotropin.