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. 2018 May 24;3(1):2381468318776634. doi: 10.1177/2381468318776634

Table 10.

Estimated Time to Achieve a 90% Reduction in HCV Prevalence Among PWID Given the Community Prevalence, Access to Harm Reduction Programs, and Access to HCV Treatment

Reference Country/City Prevalence of HCV in PWID Level of Harm Reduction Effort 90% Prevalence Decline Achieved by Treatment Level Required (Annual)
Rate per 1,000 PWID % of HCV-Infected PWIDa
Bennett, 201587 Edinburgh, UK 25% 57% OST 15 years 40 16%
Fraser, 201785 US 55.3% 40% NSP 10 years 213 34.1%
Fraser, 201785 US 55.3% 50% NSP and OST 10 years 121 20%
Fraser, 201785 US 55.3% 40% NSP 15 years 159 25%
Fraser, 201785 US 55.3% 50% NSP and OST 15 years 89 14.5%
Gountas, 201784 Greece 64% 44% OST or NSP 10 years 258 40%
Gountas, 201784 Greece 64% 44% OST or NSP 15 years 125 19.5%

OST, opioid substitution therapy; NSP, needle-syringe exchange program.

a.

In most cases this is estimated from the treatment rate per 1,000 PWID using the current prevalence rate and so it represents the fraction of HCV-positive PWID who would be treated in the first year.