FIG. 12.

Identification of HXA₃ esterified into PE in the ileum of mice after TBI. MS/MS spectrum of PE molecular species with m/z 754.58 (A) and structural formulas of HXA₃-PE species (A, insets). HXA₃-PE species originated from PEp16:0/20:4 and PEp18:0/20:4 after the addition of two oxygens. The level of HXA₃-PE in the ileum of naïve mice and mice exposed to TBI (9.5 Gy) (B). The data on the contents of esterified PE in the ileum of irradiated mice were obtained by detailed LC-MS/MS analysis (75). Data are mean ± SD, n = 4. To see this illustration in color, the reader is referred to the web version of this article at www.liebertpub.com/ars