Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jun 9;16:45–54. doi: 10.1016/j.molmet.2018.06.006

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Expression of genes involved in bile acid metabolism in the liver (A) and ileum (B) of random-fed Gcgr^−/−:Glp2r^−/−double knockout mice and their single knockout and wild-type littermates. mRNA levels of the indicated genes were assessed by real-time qPCR and normalized to Ppia and 18S rRNA levels in liver and ileum, respectively. Shown are individual data points with overlapping mean ± SD (n = 10 mice per genotype, combined from 2 independent mouse cohorts). Panels A & B: **p < 0.01 Gcgr^−/−:Glp2r^+/+vs Gcgr^+/+:Glp2r^+/+ & Gcgr^+/+:Glp2r^−/−; ***p < 0.001 Gcgr^−/−:Glp2r^+/+ vs Gcgr^+/+:Glp2r^+/+, Gcgr^+/+:Glp2r^−/− & Gcgr^−/−:Glp2r^−/−. Statistical significance was assessed by one-way ANOVA followed by Bonferroni's multiple comparison post hoc test.