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Effect of SiNPs on the JAK1/TF signaling pathway. (A) Heat map from microarray analysis of inflammation–coagulation cascade related genes. (B) qRT-PCR analysis showed that the genes involved in inflammation–coagulation response. (C,D) SiNPs activated the JAK1/TF signaling pathway in a dose-dependent manner. n = 50, data are expressed as mean ± standard deviation from three independent experiments (*p < 0.05).
