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. 2018 Sep 19;14:2389–2399. doi: 10.2147/NDT.S176047

Table S1.

Correlations between neurosteroid serum levels, cognitive function, and quality of life in older female subjects (>35 years old, N=40)

DHEA
DHEA-S
Pregnenolone
r P-value r P-value r P-value
Cognitive function (BACS)
 Verbal memory 0.02 0.904 0.166 0.307 0.086 0.599
 Working memory 0.175 0.281 0.448 0.004a −0.008 0.959
 Motor speed −0.057 0.726 0.074 0.648 −0.074 0.652
 Verbal fluency −0.248 0.122 0.151 0.352 0.184 0.257
 Attention and processing speed −0.134 0.411 −0.01 0.949 0.172 0.288
 Executive function −0.123 0.451 0.092 0.574 0.344 0.03a
 Composite score of the BACS −0.059 0.719 0.273 0.088 0.219 0.175
Quality of life (WHOQOL-BREF)
 Physical health −0.018 0.914 −0.065 0.691 0.044 0.786
 Psychological health 0.1 0.537 0.172 0.289 −0.007 0.967
 Social relations −0.003 0.985 0.032 0.842 0.047 0.774
 Environment −0.022 0.893 −0.112 0.493 −0.157 0.334

Notes: Data are computed using Pearson Correlation.

a

P<0.01.

Abbreviations: BACS, the Brief Assessment of Cognition in Schizophrenia; DHEA, dehydroepiandrosterone; DHEA-S, dehydroepiandrosterone-sulfate; WHOQOL-BREF, the brief version of the World Health Organization Quality of Life.