Table S2.
Correlations between neurosteroid serum levels, cognitive function, and quality of life in older female subjects (≥35 years old, N=35)
| DHEA
|
DHEA-S
|
Pregnenolone
|
||||
|---|---|---|---|---|---|---|
| r | P-value | r | P-value | r | P-value | |
| Cognitive function (BACS) | ||||||
| Verbal memory | −0.233 | 0.178 | 0.022 | 0.902 | −0.075 | 0.67 |
| Working memory | 0.092 | 0.598 | 0.208 | 0.231 | −0.018 | 0.917 |
| Motor speed | 0.014 | 0.938 | −0.072 | 0.683 | 0.244 | 0.158 |
| Verbal fluency | −0.014 | 0.937 | 0.183 | 0.292 | 0.196 | 0.259 |
| Attention and processing speed | −0.191 | 0.271 | 0.032 | 0.853 | 0.032 | 0.856 |
| Executive function | −0.067 | 0.7 | 0.273 | 0.112 | 0.034 | 0.845 |
| Composite score of the BACS | −0.08 | 0.648 | 0.184 | 0.291 | 0.159 | 0.361 |
| Quality of life (WHOQOL-BREF) | ||||||
| Physical health | −0.157 | 0.368 | 0.001 | 0.996 | −0.045 | 0.796 |
| Psychological health | −0.028 | 0.875 | 0.037 | 0.834 | 0.075 | 0.668 |
| Social relations | −0.141 | 0.42 | 0.084 | 0.63 | −0.028 | 0.872 |
| Environment | −0.061 | 0.729 | −0.009 | 0.959 | −0.062 | 0.723 |
Note: Data are computed using Pearson Correlation.
Abbreviations: BACS, the Brief Assessment of Cognition in Schizophrenia; DHEA, dehydroepiandrosterone; DHEA-S, dehydroepiandrosterone-sulfate; WHOQOL-BREF, the brief version of the World Health Organization Quality of Life.