Table 3.

Correlations between neurosteroid serum levels, cognitive function, and quality of life in male subjects (N=47)

	DHEA		DHEA-S		Pregnenolone
	F	P-value	F	P-value	F	P-value
Cognitive function (BACS)
Verbal memory	0.633	0.431	0.437	0.512	1.336	0.255
Working memory	0.278	0.601	5.034	0.031a	4.446	0.041a
Motor speed	0.012	0.912	1.331	0.256	1.387	0.246
Verbal fluency	1.878	0.178	3.446	0.071	5.299	0.027a
Attention and processing speed	1.070	0.307	0.092	0.763	0.679	0.415
Executive function	0.055	0.816	0.150	0.701	0.575	0.453
Composite score of the BACS	0.014	0.906	2.527	0.120	5.887	0.020a
Quality of life (WHOQOL-BREF)
Physical health	5.034	0.031a	0.998	0.324	0.034	0.856
Psychological health	2.028	0.162	0.193	0.663	0.179	0.675
Social relations	4.215	0.047a	0.030	0.862	2.007	0.164
Environment	10.172	0.003a	0.256	0.615	0.814	0.373

Notes: Data are computed using MANCOVA, controlling for age and educational level.

^aP<0.05.

Abbreviations: BACS, the Brief Assessment of Cognition in Schizophrenia; DHEA, dehydroepiandrosterone; DHEA-S, dehydroepiandrosterone-sulfate; MANCOVA, multivariate analysis of covariance; WHOQOL-BREF, the brief version of the World Health Organization Quality of Life.