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. 2018 Sep 19;5:257. doi: 10.3389/fmed.2018.00257

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Copyright © 2018 Campbell.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Sites of cleavage of bradykinin by different enzymes. ACE, angiotensin converting enzyme; ECE-1, endothelin converting enzyme-1; ECE-2, endothelin converting enzyme-2; NEP2, neprilysin homolog membrane metalloendopeptidase-like 1. (2–5, 7, 25–28, 30, 32–38).