Table 3.
Pathological and clinical tumor response
| Efficacy | TCH (N=39) | XEC-XT (N=33) | FEC-T (N=32) | TEC (N=35) | P-value |
|---|---|---|---|---|---|
| pCR | 10 (25.6%) | 6 (18.2%) | 2 (6.3%) | 7 (20%) | 0.041 |
| PR | 24 (61.5%) | 20 (60.6%) | 18 (56.2%) | 19 (54.3%) | 0.784 |
| SD | 5 (12.8%) | 7 (21.2%) | 10 (31.3%) | 9 (25.7%) | 0.102 |
| PD | 0 (0%) | 0 (0%) | 2 (6.2%) | 0 (0%) | 0.136 |
| ORR | 34 (87.1%) | 26 (78.7%) | 20 (62.5%) | 26 (74.3%) | 0.107 |
Note: P-value by chi-squared test or Fisher’s exact test when the cell expectation was less than six.
Abbreviations: pCR, pathological complete response; PD, progressive disease; PR, partial response; ORR, objective remission rate; SD, stable disease; FEC, 5-fluorouracil/epirubicin/cyclophosphamide; TCH, docetaxel, carboplatin and trastu-zumab; TEC, docetaxel, epirubicin and cyclophosphamide; XEC, capecitabine/epirubicin/cyclophosphamide.