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. Author manuscript; available in PMC: 2019 Jul 28.
Published in final edited form as: J Control Release. 2018 Apr 27;282:110–119. doi: 10.1016/j.jconrel.2018.04.045

Figure 1. Physiochemical characterization of lyophilized MK2i-NP formulations with and without excipients.

Figure 1

A) The concentration dependent-effects of various excipients on the size of lyophilized MK2i-NPs. For A, n = 3 independent MK2i-NP formulations and measurements. (* p < .005, ** p < .001) B) TEM images for freshly prepared MK2i-NPs, lyophilized MK2i-NPs without excipient, and MK2i-NPs lyophilized in 150 mM and 300 mM lactosucrose. Ctrl = excipient without polyplexes