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. Author manuscript; available in PMC: 2019 Jul 28.
Published in final edited form as: J Control Release. 2018 Apr 27;282:110–119. doi: 10.1016/j.jconrel.2018.04.045

Figure 2. Excipients Improve the Cellular Uptake of MK2i-NPs in HCAVSMCs.

Figure 2

A) Concentration dependent effects of excipients on the uptake of fluorescent, lyophilized MK2i-NPs in HCAVSMCs (n = 3; * p < 0.05, ** p < 0.01, *** p < 0.005, **** p < 0.001) B) Representative histograms of the cellular uptake of freshly prepared and lyophilized MK2i-NP formulations with and without 300 mM lactosucrose in HCAVSMCs. C) Representative confocal microscopy images of the cellular uptake of freshly prepared and lyophilized MK2i-NP formulations with and without 300 mM lactosucrose in HCAVSMCs. NT = no treatment, Ctrl = excipient without polyplexes.