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. 2018 Aug 30;9(9):4552–4568. doi: 10.1364/BOE.9.004552

Table 5. Advantages and disadvantages of mid-IR lasers for lithotripsy.

Laser Advantages Disadvantages
TFL: (1) 4x lower ablation threshold than Ho:YAG (1) Experimental laser, capital cost TBD
(2) Use with smaller fibers (50-150 µm core) (2) Clinical studies still lacking
(3) High pulse rates (1-2000 Hz) for dusting
(4) High wall plug efficiency (~12%); air-cooled
Tm:YAG: (1) Diode-pumped laser (1) Limited testing, few publications on feasibility
(2) Continuous-wave laser, needs to be modulated
Ho:YAG: (1) Clinically proven to fragment all stone types (1) Does not closely match water absorption peak
(2) Low capital cost for low power lasers (2) Limited to use with fibers ≥ 200-µm-core
(3) Limited to low pulse rates (5-80 Hz)
(4) High maintenance costs
(5) Low wall-plug efficiency(1-2%); water cooling
Er:YAG: (1) Higher ablation rates than Holmium (1) No fiber optic delivery system that is low cost, biocompatible, flexible, and robust
(2) Limited to low pulse rates