Table 1.
Characteristics of included studies in this meta-analysis
| Reference | Study interval | Cohort type | Country | Total cases | Number (MIME/MILE) | Gender (male) (MIME/MILE) | Location of cancer | Age (MIME/MILE) | AJCC staging
|
Anastomotic leak
|
Mortality
|
|||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0, I, and II (MIME/MILE) | III and IV (MIME/MILE) | MIME | MILE | MIME | MIE | |||||||||
| Luketich et al,9 2012 | 1996–2011 | Retrospective | USA | 1,011 | 481/530 | 392/415 | All segments | 65 (56–72)/64 (56–72)a | NA | NA | 26/481 | 23/530 | 12 | 5 |
| Brown et al,10 2017 | 2011–2016 | Prospective | USA | 110 | 61/49 | 51/40 | All segments | 63.0±8.7/60.9±9.0 | 41/26 | 20/23 | 5/61 | 2/49 | 1 | 3 |
| Hao et al,17 2014 | 2008–2012 | Retrospective | People’s Republic of China | 136 | 81/55 | NA | All segments | NA | NA | NA | 4/81 | 0 | NA | NA |
| Nguyen et al,18 2008 | 1998–2007 | Prospective | USA | 98 | 47/51 | 39/33 | All segments | 65±10/64±12 | NA | NA | 3/47 | 5/51 | 2 | 1 |
| Chen et al,19 2017 | 2014–2016 | Prospective | People’s Republic of China | 251 | 51/200 | 38/169 | All segments | 61.4±9.1/59.9±8.4 | 29/110 | 22/99 | 4/51 | 1/200 | 1 | 0 |
| Hou et al,20 2017 | 2014–2016 | Retrospective | People’s Republic of China | 185 | 65/120 | 41/82 | All segments | 56.7±11.6/57.2±13.0 | 46/88 | 19/32 | 8/65 | 3/120 | 1 | 1 |
| Zhai 201521 | 2013–2015 | Retrospective | People’s Republic of China | 72 | 40/32 | 37/28 | Middle and low segments | 60.0±6.9/60.0±9.1 | 31/27 | 9/5 | 12/40 | 3/32 | NA | NA |
| Wu et al,22 2014 | 2011–2014 | Retrospective | People’s Republic of China | 357 | 138/219 | 106/169 | Middle and low segments | 63.5±17.6/61.8±18.5 | NA | NA | 20/138 | 13/219 | 3 | 4 |
| Lin et al,23 2014 | 2010–2014 | Retrospective | People’s Republic of China | 288 | 185/103 | 142/80 | Middle and low segments | 58.3±8.7/59.1±8.4 | 89/65 | 96/38 | 24/185 | 2/103 | 1 | 0 |
| Mei et al,24 2016 | 2012–2015 | Retrospective | People’s Republic of China | 106 | 65/41 | 49/32 | Middle and low segments | 62.7±5.0/63.56±5.1 | 46/32 | 19/9 | 12/65 | 2/41 | NA | NA |
| Wei 201625 | 2013–2015 | Retrospective | People’s Republic of China | 120 | 50/70 | 47/23 | Middle and low segments | 59.7±8.3/55.7±6.2 | 43/59 | 7/11 | 6/50 | 0/70 | NA | NA |
| Rajan et al,26 2010 | 1997–2009 | Retrospective | India | 336 | 319/17 | NA | All segments | NA | NA | NA | 5/319 | 1/17 | 4 | 0 |
| Schmidt et al,27 2017 | 2011–2016 | Retrospective | Switzerland | 334 | 146/188 | NA | All segments | NA | NA | NA | 25/146 | 26/188 | 2 | 1 |
| Chang et al,28 2018 | 2015 | Retrospective | People’s Republic of China | 53 | 33/20 | NA | All segments | NA | NA | NA | 4/33 | 4/20 | 1 | 0 |
Notes: Age (years) was reported mostly as the mean ± SD.
a
The study reported age as median (interquartile range). Mortality here means 30-day/in-hospital mortality.
Abbreviations: AJCC, American Joint Committee on Cancer; MILE, minimally invasive Ivor Lewis esophagectomy; MIME, minimally invasive McKeown esophagectomy; NA, not available.